FITNESS FOR SERVICE AND RELIABILITY OF MATERIALS FOR MANUFACTURING COMPONENTS INTENDED FOR DEMANDING SERVICE CONDITIONS IN THE PETROCHEMICAL INDUSTRY

Fitness for Service and Reliability of Materials for Manufacturing Components Intended for Demanding Service Conditions in the Petrochemical Industry

A methodology has been developed to quantitatively assess the suitability of use and fitness for service of candidate materials using a novel approach that includes multiple perspectives.As a case study, a carbon steel pipe has been selected for operation in the petrochemical sector.The materials studied were the following: American Petroleum Insti

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In-frame amber stop codon replacement mutagenesis for the directed evolution of proteins containing non-canonical amino acids: identification of residues open to bio-orthogonal modification.

Expanded genetic code approaches are a powerful means to add new and useful chemistry to proteins at defined residues positions.One such use is the introduction of non-biological reactive chemical handles for site-specific biocompatible orthogonal conjugation of proteins.Due to our currently limited information on the impact of non-canonical amino

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